The National Institute of Diabetes and Digestive and Kidney Diseases
R01 MH125187 (PI: Rumbaugh and Xu)
Molecular and cellular basis for autism spectrum disorders caused by exacerbated translation
The major goal of this project is to investigate how elevated protein synthesis in microglia leads to autism-like synaptic and behavioral abnormalities in mice.
R01 DK103335 (PI: Xu)
Unraveling the role of PVH BDNF neurons in energy balance
The major goals of this project are to determine the role of BDNF-expressing neurons in the paraventricular hypothalamus in the control of food intake and energy expenditure and to elucidate the neural circuits linking these neurons.
R01 DK105954 (PI: Xu)
TrkB neurons in the control of body weight
The major goals of this project are to investigate the role of TrkB-expressing neurons in the paraventricular hypothalamus and the dorsomedial hypothalamus in the regulation of food intake and energy expenditure, to elucidate the neural circuits linked to these neurons, and to molecularly characterize these neurons.
R01 DK112759 (PI: Yang)
Astrocytic target mechanisms in obesity
The major goals of this project are to investigate the role of astrocytes in the control of food intake and energy expenditure by modulating the function of neurons in the arcuate nucleus of the hypothalamus.